The overarching theme of this project is to get ready for LDMX data, and the work will be conducted in close connection with the international LDMX collaboration, in which Lund University is the only non-US participant for the time being. One exciting milestone for LDMX is a beam test planned at SLAC in 2025, for the first time collecting data at the actual beam line for LDMX. During the first year, roughly, this project will be focused on the gathering and in particular on the analysis of this test beam data, mainly from the prototype of the hadronic calorimeter.

Another priority in this project will be to study the capabilities of LDMX to handle pile-up (multiple electrons hitting the target at the same time) in more detail. This will mainly be based on simulations studies of potential backgrounds, detector performance, and physics sensitivities. One concrete example is the use of different codes for simulating critical backgrounds, to compare these predictions and to develop methods for how to measure these backgrounds in data. The project also aims to explore to which extent machine learning methods can help with these tasks, e.g. object reconstruction and signal vs background discrimination. This will become more of a focus  later in the project.

This post-doctoral position is part of the EU cofund research project AMBER, Advanced Multiscale Biological imaging using European Research infrastructures, will address scientific and sectoral gaps in biological imaging ranging from molecular, through cellular, to tissue, organ and organism levels of organisation, and is coordinated by LINXS Institute of advanced Neutron and X-ray Science.

AMBER is funded by the EU Marie Skłodowska-Curie (MSCA) COFUND scheme. Around 14 postdocs will be recruited in the first call, with each fellowship lasting 36 months.

AMBER has six core partners: Lund University/MAX IV, Sweden, the European Spallation Source (ESS), Sweden, the European Molecular Biology Laboratory (EMBL), Institut Laue-Langevin (ILL), France, the International Institute of Molecular Mechanisms and Machines, (IMOL), Poland, and the Leicester Institute of Structural and Chemical Biology, United Kingdom.

The membrane protein structural biology group at the Department of Experimental Medical Science is at the forefront of its field. With this position, we aim to deepen our work in understanding the mechanisms of various P-type ATPases. The research group is led by senior lecturer Pontus Gourdon, and we are now seeking a motivated postdoctoral researcher with experience in cryo-electron microscopy. Here is a selection of articles recently published by the group (see also tinyurl.com/vc2dsamz):

• Li et al (2024) Nature Communications 15(1):9605
• Augestad et al (2024) Nature 633:704
• Guo et al (2024) Nature Communications 15(1):2690
• Zhang et al (2022) Nature Communications 13(1):7483
• Salustros et al (2022) Nature Communications 13(1):5121
• Li et al (2022) Nature Communications 13(1):4339
• Wiuf et al (2022) Science Advances 8, eabn4331

A highly motivated postdoctoral scientist is sought to work on a project designed to extend our understanding of the molecular basis of transthyretin amyloidosis Read more here. Human transthyretin (TTR) is a protein that transports thyroxine and retinol-binding protein (RBP) in the serum and cerebrospinal fluid. Wild-type TTR is intrinsically amyloidogenic, but a large number of TTR mutants have been identified that are associated with early-onset amyloidosis and where there are remarkable tissue specificities.  This project seeks to gather atomic/molecular level information  on different TTR mutants using crystallography (X-ray and neutron), cryo-EM, and a wide range of other biophysical techniques. It will make use of the MAX-IV and ESS facilities in Sweden as well as the ESRF and ILL X-ray/neutron sources in Grenoble, France. Where possible it is planned  to carry out comparative studies of amyloid material derived from in vitro and ex vivo sources. The project will have good access to state-of-the-art facilities within the medical, natural science and engineering faculties, as well as being located in close proximity to the nearby MAX-IV synchrotron and ESS neutron beam facilities on the Science Village campus near the Lund city centre.

Heart attacks and strokes are the largest causes of death and disability in the world. Atherosclerosis, the disease that underlies most of these cardiovascular events, consists on the formation of plaques (accumulations of lipids and inflammatory cells) in the arterial walls. When these plaques rupture, subsequent thrombosis occurs cause those events. The plaques that are prone to rupture seem to have a particular composition that is currently difficult to identify with clinical methods and that is still largely unknown due to an enormous complexity.

Human plaque components such as lipid cores, necrosis/apoptosis, intra plaque-hemorrhage, thin fibrous cap, inflammation, micro and macro calcifications, damaged collagen and/or elastic fibers are highly relevant for the risk of rupture. However, many of these components are difficult to study by conventional methods as histology. Therefore, nondestructive methods, with high-resolution as synchrotron-based technologies create unique opportunities to study these complex atherosclerotic plaques, which are the largest killers all over the world.

The tasks include participating in research projects focusing on molecular imaging of metabolic processes in healthy and pathological cells, as well as developing methodological aspects within the metabolic field. The work will encompass clinical and biomedical projects and may also include technology development aimed at integrating experimental techniques in the metabolic field with data analysis to provide a more comprehensive view of molecular processes related to health and disease.

A highly motivated postdoctoral scientist is sought to work on a project designed to extend our understanding of the molecular basis of aquaporins (AQPs). AQPs are evolutionary conserved transmembrane proteins that are responsible for water and glycerol regulation in the human body, but also in many other organisms. Besides solute transport, AQPs have been shown to be involved in cellular signaling, cell migration, and cell-cell adhesion. For instance, AQPs are the main glycerol channel in the endocrine pancreas, mediating rapid flux of glycerol in β-cells and ultimately insulin secretion. Interestingly, it was also recently reported that AQPs in fruit flies have a central role in metabolism. The overall goal of the project is to study the structure of aquaporins using single particle cryo-EM and combine that with functional studies at the cellular level to resolve its mechanism of action. In addition, AQPs are therapeutic targets, thus the project will also include the development of putative AQP blockers, that can be used for treating diseases and/or to selectively kill insects expressing aquaporins.  The project will have good access to state-of-the-art facilities within the medical, natural science and engineering faculties, as well as being located in close proximity to the nearby MAX IV synchrotron where also the Lund cryo-EM facility is situated.

Bacteria are constantly predated by viruses, bacteriophages. To resist predation, bacteria employ numerous antiphage defence systems, with the most famous being CRISPR-Cas. In our lab we discover new systems with bioinformatics, validate them in microbiological assays and then characterise the mechanisms of defence on the molecular level. Currently the lab is working on many (>10) novel, as-yet-unpublished antiphage defence systems. The focus of this project would be to uncover their molecular workings through integrated structure-functional approach combining phage microbiology, biochemistry and structural biology. The project is supervised by Vasili Hauryliuk (PI) as well as Gemma Atkinson (co-PI, structural bioinformatics, Lund University) and Pontus Gourdon (co-PI, cryo-EM, Lund University and University of Copenhagen).

The position is placed at the Division of Solid State Physics at the Department of Physics, a division with around 100 employees where extensive research is carried out centered on various aspects of nanophysics, ranging from materials science to bio- and quantum physics to various applications. The division is a central part of NanoLund, Lund University’s large interdisciplinary research Centre on nanoscience and nanotechnology.

A significant part of the research at the division is in characterization of semiconductor materials. The department hosts the research group of Prof Vanya Darakchieva. Together with its co-operating partners, the group has developed in recent years THz ellipsometry and its applications in characterization of semiconductor materials and devices. The optical Hall effect is one of the advanced characterizations to access electronic transport properties. The method has been applied to two-dimensional semiconductor systems such as nitride-based high electron mobility transistors and graphene, but also to large band gap and low symmetry semiconductors such as Ga2O3. These materials and components lay the foundation for the next generation of high-frequency and high-power electronics being developed together with leading Swedish industrial partners.

Private international law consists of legal norms which regulate relationships between international private legal subjects which are based on voluntary legal acts. The topic carbon capture and storage (CCS) is at the crossroads of law, governance, sustainability and technology and involves subjects of both public and private law.Transboundary alternatives for CO2 transport and offshore storage are necessary preconditions for the viability of CCS. Once the carbon is captured, the transportation (national and transboundary) can take place by road, rail, ships or pipes.

The post-doctoral position is situated within the project titled “Sustainable Carbon Capture Transportation and Storage: Liability and Governance in Light of International and EU Law.” It addresses the emerging practise of mitigating greenhouse gas emissions through innovative CCS technologies. With a special focus on the transportation of carbon streams by ships, the project relates to the potential liabilities arising during carbon transportation by ship and the implications for long-term liability.

At the Division of Combustion Physics a postdoc is now recruited for the European Union Project CAIPIRINH3A. The main goal of the research performed at our Division within this project is to provide a detailed kinetic mechanism and perform reliable modeling studies for NOx prediction and control in NH3 combustion applications. Experimental results used to validate the numerical model will be based on flame structure measurements of NH3 flames at atmospheric pressure employing Raman spectroscopy arranged with multiple laser beam passages for high detection sensitivity, as well as time-resolved optical emission spectroscopy from ammonia flames after a single pulse nanosecond discharge. The validated mechanism will be incorporated in dedicated global solvers (incorporating plasma effects) which will be used to calculate fundamental combustion characteristics of ammonia/air mixture with and without plasma. The kinetic model will be tested against results from these experiments, other results obtained by the project partners and literature data and will output different characteristics of NH3 combustion including burning velocities, ignition delay times, species profiles in flames, chemiluminescence in thermal and plasma-affected flames.

The Acoustofluidics Group at the Department of Biomedical Engineering mainly focuses on the emerging field of combining ultrasonics and microfluidics for particle and fluid manipulation in micro- and nanoscale, and it is one of the world-leading groups in this field. The interdisciplinary research carried out in the group ranges from theoretical work in acoustics, fluid mechanics and multibody dynamics to the applications in biomedicine. The group consists of a diverse range of researchers, from senior professors to junior PhD students. The group strives for an inclusive environment, based on collaboration and trust, where development towards an independent researcher is encouraged and supported. More information can be found on the website: Nanobiotechnology and Lab-on-a-chip.

This employment is placed at the Department of Biomedical Engineering, Lund University, and the project will be carried out within a consortium supported by the European Innovation Council. The appointed postdoctoral fellow is expected to join the regular meetings held by the members of the consortium, which spans groups from ETH Zürich, the University of Bern, the University of Barcelona, and the University of Münster.

In the Perinatal and Cardiovascular Epidemiology (PACE) research group we work cross-disciplinary to improve our understanding of pregnancy complications, particularly preeclampsia, and cardiovascular disease. We also have a substantial methodological interest and expertise, which further adds variety to the research questions we pursue. The research group is led by Simon Timpka (Associate Professor in Clinical Epidemiology) and consists of >10 members, most of whom work part-time as clinicians. Our offices are located at the Clinical Research Center (CRC) in Malmö, next door to the Department of Obstetrics and Gynecology at Skåne University Hospital. We employ a full-time senior PhD statistician and many of our projects leverage large sets of registry-based and/or biomarker data. Our recent research output has resulted in publications in e.g. JAMA (Lawesson et al., 2023), Hypertension (Mattsson et al., 2024), and Journal of Internal Medicine (Enhörning et al., 2022).

RIANA is a project under Horizon Europe, aiming to advance research in the fields of nanoscience and nanotechnology. 69 European research infrastructures have joined forces to create a unique platform to cover the most advanced techniques relevant for synthesis, nanofabrication, processing, characterization, analytics, and simulations for advancement in nanoscience and nanotechnology. You will be responsible for supporting user projects in this field with SAXS/WAXS (both transmission and grazing incidence) as a part of a group of junior scientists within the project. The RIANA project is a great opportunity to build up a network within other research infrastructures and an opportunity to learn about other techniques.

The Department of Electrical and Information Technology at Lund University houses a wide range of research groups, including those that focus on internetconnected systems and wireless communication. Positioned at the intersection of these two areas and within the Division of Secure and Networked Systems, this position offers an opportunity to work on integrating advanced wireless technology with innovative computing to shape the future of 6G-communications system.

The department offers a collaborative and inclusive culture that promotes creativity, initiative and interdisciplinary thinking. You will be part of a team committed to high-impact research, where theoretical insights are combined with practical applications, in an environment that values ​​innovation, supports professional development and encourages a good work-life balance. This environment is ideal for those who enjoy solving complex problems and pushing the boundaries of what is possible in real-time, low-latency applications.

MAX IV is looking for a postdoctoral researcher for an initial appointment of 2 years. As a member of the Bloch team, you will contribute to the beamline activities, working to ensure that user beamtimes are as productive as possible and that scientists feel excited when they receive an opportunity to come here. This requires from the beamline team a very strong focus on maintaining the performance of the equipment while simultaneously developing and commissioning new capabilities, new control and analysis software and new research projects. This often occurs in close collaboration with support functions at MAX-IV and external user groups.
As a postdoc at the beamline you will operate within and contribute to this environment, but your principle mandate will be to design and execute an independent research program, to which you will dedicate approximately 50% of your working time. You will have access to a fraction of the in-house beamtime allocation for this, and will also be expected to obtain additional time both at Bloch and elsewhere through conventional competitive beamtime applications.

Physical Chemistry involves research relating to molecular issues. The experimental and theoretical methods used often originate from physics. The emphasis in Physical Chemistry at the Department of Chemistry is on research, both experimental and theoretical, within surface and colloidal chemistry and with a special focus on self-aggregating systems. The systems studied include surfactants, polymers and biomolecules.

This project introduces silicon substrates with a switchable magnetic contrast layer (MCL) for polarised neutron reflectometry experiments (PNR) at solid/liquid interface to study soft matter surface layers. The structural and compositional information in a typical reflectometry experiment are obtained by collecting experimental data with different isotopic contrasts on the same sample. This approach is normally referred to as contrast matching, which can be achieved by using solvents with different isotopic contrast, e. g. different H2O/D2O ratio, and/or by selective deuteration of the molecules. However, some soft matter systems might be perturbed by this approach, or it might be difficult to implement, particularly in the case of biological samples. Here solid substrates with a MCL are an appealing alternative, as the magnetic contrast with the substrate can be used to partially recover the information on the sample structure. The project is part of a larger collaborative project, “Maximizing information content in neutron reflectivity data by optimised magnetic reference layers” between Linköping, Uppsala and Lund universities, Science and Technology Facilities Council, ISIS Neutron and Muon Sourcs, Rutherford Appleton Laboratory in UK and European Spallation Source – ESS, financed by the Swedish Research Council.

The post-doctoral position is placed at the division of Combustion Physics. The aerosol research group at combustion physics conducts research on atmospheric aerosol particles and their impact on climate and air quality. This research involves aerosol in-situ measurements, satellite measurements, process modelling and global modelling. The research group is part of the strategic research area MERGE (https://www.merge.lu.se) that work with climate modelling. Aerosol research has been conducted at Lund University since the 1970-ies and Aerosols is now a profile area at the Faculty of Engineering (https://www.lth.se/english/research/profile-areas/aerosols/).  

Combustion physics has approximately 70 employees and is located in the Enoch Thulin-laboratory at the Physics Department. The division actively works to create a friendly working environment and has a well-being group that arranges board game nights, excursions, and other activities.

The focus of this project is nanomaterials to be used in neuromorphic devices for artificial intelligence (AI). AI is a key technology for the transition to a carbon-neutral society but relies on powerful computing hardware which high energy consumption is itself a difficult obstacle on the road to sustainable AI. Inspired by the brain, neuromorphic hardware promises up to 1,000 times more energy-efficient computing by interweaving computation with data storage. The key to this breakthrough technology is new types of nanoelectronic memory devices that require research in terms of the materials that they are built by.

The primary goal of this project is to investigate the detailed chemistry of combustion of different sustainable aviation fuels (SAF) suggested for replacing fossil fuels focusing on the formation and abatement of pollutants that could potentially be formed. The motivation for this is the development of a long-term solution for sustainable and environmentally friendly aviation. The key research question of the present project is the impact of super adiabatic phenomena on formation of different pollutants. Overall planning is arranged around several commercially approved SAF, and surrogate mixtures reproducing their physical characteristics. The work program includes experimental research, development of detailed kinetic models and reduced models suitable for CFD modelling.

In the biopharmaceutical industry it is common practice to produce the pharmaceutical proteins, and then dry them for safe storage until the final products are manufactured. At present, lyophilization is the gold standard, but it would be beneficial to be able to dry these proteins using spray-drying. However, at the early development stages when only small quantities of the protein are available, current lab-scale spray-drying requires too much material for assessment of processability. 

Therefore, this project will develop a miniaturized spray-dryer that emulates the lab- and pilot scale process regarding thermal load and other stresses. A second objective is to assess the effects of spray-drying on the protein structure, and the mechanisms behind such changes. Ultimately, this may allow for prediction of processabilty based on protein sequence and structure.